Bacteria have a hard life. All they ever think about is survival and propagating across anything they touch. Until now! Your species has developed psychic powers - and debatable levels of intelligence. Now, it's your job to command, control, and conquer everything in sight.

Control your mutation tendencies: Prioritize between speed of reproduction, combat power, mutation rate, cooperation, and psychic strength. Everything is important - but the right ratio depends on the situation.
Rule the petri dish with psychic powers: Gain abilities to control any situation - delve into information, enhance yourself, destroy your enemy (and yourself) in droves, alter your environment, and even control fate.
Use the tiny terrain to your advantage: Every obstacle can be overcome, bypassed, or used to blockade the enemy. You can use what is given to you or even better, make your own!
Advance to learn the epic plot line: All right, it's not very epic. What do you expect? You're bacteria! Even so, your microbial world is threatened, and it's up to you to do something!
Overcome challenges to earn upgrades: Push through difficult situations, limit your power while succeeding, or solve intricate puzzles and mysteries. Each of these can grant access to lasting upgrades that can be used on all future games.
But wait, there's more!: Still not done? Still not HARD ENOUGH? Play (or replay) with increased difficulty, opening even more upgrades.

Hard: win Petri Dish time runs out

Normal: win Lollipop without changing mutation rates

Hard: win Petri Dish time runs out

Normal: win Lollipop without changing mutation rates

Hard: win One V Four before time runs out

Normal: win Disks without using Encyst

Win Pockets without any combat

Hard: win Ascus without filling bottom right corner

Normal: win Snails without filling left snail center

Win Planets without using Fragment

Hard: win Escape before time runs out

Normal: win Cork without using Mutate